Translational Medicine: Definition, History, and Strategies
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CALL FOR PAPERS Sex and Gender Differences in Cardiovascular Physiology–Back to the Basics Why are sex and gender important to basic physiology and translational and individualized medicine?
Miller VM. Why are sex and gender important to basic physiology and translational and individualized medicine?. Am J Physiol Heart Circ Physiol 306: H781–H788, 2014. First published January 10, 2014; doi:10.1152/ajpheart.00994.2013.— Sex refers to biological differences between men and women. Although sex is a fundamental aspect of human physiology that splits the population in two approximatel...
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There is growing evidence to the importance of translational science and medicine in the improvement of patient outcome, even though the definitions of translational science, translational medicine, and clinical and translational medicine need to be further clarified. In the present perspective, we collected commentaries and descriptions about clinical and translational medicine from some membe...
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Translational medicine is a branch of medical research that attempts to more directly connect basic research to patient care. Translational medicine is growing in importance in the healthcare industry, and is a term whose precise definition is in flux. In the case of drug discovery and development, translational medicine typically refers to the “translation” of basic research into real therapie...
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What is translational medicine? This question has been vigorously debated by various constituencies for many years. One recent, encompassing definition of translational medicine was developed for the Strategic Plan in service of the American Society for Clinical Pharmacology and Therapeutics (ASCPT).1,2 Not coincidentally, the ASCPT Strategic Plan was aptly entitled “Transforming Translation.”
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Along with scientific and regulatory issues, the translation of cell and tissue therapies in the routine clinical practice needs to address standardization and cost-effectiveness through the definition of suitable manufacturing paradigms.
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